Achelios Therapeutics, Inc., is a Chapel Hill, North Carolina based specialty pharmaceutical company with primary focus on “New Therapeutic Entity” (NTE) development for the treatment of pain and inflammation by topically delivered medications. Achelios Therapeutics is currently focusing its resources on its most advanced product, TOPOFEN™, for the indication of acute migraines. We believe we have found the solution to a problem that has plagued other industry players for a number of years: how to successfully transfer efficacious amounts of active non-steroidal anti-inflammatory drugs (NSAIDs) through the dermis to the target tissue.